Description
Description
Tetrahexyldecyl Ascorbate (THD Ascorbate) is a lipophilic tetraester derivative of vitamin C designed for incorporation into oil phases, anhydrous systems, and premium emulsions. Its oil compatibility differentiates it fundamentally from L-ascorbic acid and water-soluble ascorbate salts, allowing formulators to build vitamin C systems without relying on strongly acidic aqueous architecture.
Chemical & Technical Profile
INCI: Tetrahexyldecyl Ascorbate. CAS No.: 183476-82-6. Molecular formula: C70H128O10. Molecular weight: approximately 1129.8 g/mol. Physical form: clear, colorless to slightly yellow liquid. Functional class: oil-soluble vitamin C derivative / skin-conditioning antioxidant active. The material is insoluble in water and should be incorporated through an oil-compatible carrier or lipid phase.
Mechanism of Action
THD Ascorbate functions as an esterified vitamin C precursor. Following appropriate biological processing, the ascorbate moiety can contribute to vitamin C-related antioxidant and skin-conditioning pathways. Commercial technical data also position THD Ascorbate for reduction of reactive oxygen species and UV-induced melanogenesis. Because the molecule is highly lipophilic, its formulation behavior and delivery profile differ substantially from free L-ascorbic acid.
Formulation Guidelines
Incorporate into the oil phase, an anhydrous carrier, or a compatible emollient premix. Avoid unnecessary prolonged heating and minimize oxidative exposure during processing. In emulsions, confirm that the selected active level does not destabilize oil-phase loading, droplet structure, viscosity, or sensory profile. It can be combined with compatible emollients, tocopherols, ceramide systems, and other lipid-soluble antioxidants where the complete system remains physically and chemically stable.
Compatibility & Stability
Although more formulation-flexible than free ascorbic acid, THD Ascorbate is not chemically inert. Monitor color development, odor, oxidation, phase separation, and active stability. Antioxidant support and protective packaging remain important, particularly in high-active or highly unsaturated oil systems.
R&D, Scale-Up & Quality Control
For Tetrahexyldecyl Ascorbate (THD), incoming and in-process QC should control identity, color, odor, oil-phase clarity, and oxidative change.
Packaging, Shipping & Storage
Supplied in a tightly sealed, light-protective container. Store closed, away from direct light and excessive heat. Prevent repeated air exposure during handling.
Applications
Facial oils, anhydrous serums, emulsions, moisturizers, eye care, brightening systems, and premium age-support formulations.






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