Description
Description
Kojic Acid is a fungal-derived pyrone compound widely used in tone-evening formulations. Its technical importance comes from the hydroxypyrone ring, which can coordinate copper ions at the catalytic center of tyrosinase. The ingredient is highly water-compatible but more chemically fragile than its simple handling might suggest.
Chemical & Technical Profile
| INCI / Identity | Kojic Acid |
|---|---|
| CAS No. | 501-30-4 |
| Molecular Formula | C6H6O4 |
| Molecular Weight | 142.11 g/mol |
| Physical Form | White to off-white crystalline powder |
| Solubility | Soluble in water and alcohol |
| Functional Category | Tyrosinase-chelating skin-conditioning active |
Mechanism of Action / Technical Function
Kojic Acid inhibits tyrosinase primarily by chelating copper within the enzyme’s active site, thereby reducing catalytic oxidation of tyrosine-derived substrates required for melanin synthesis. This metal-chelation mechanism is distinct from exfoliating acids and complements actives that influence melanosome transfer or melanogenic signaling.
Formulation Guidelines
Dissolve in purified water or a controlled aqueous premix. Maintain a mildly acidic formulation environment and avoid prolonged high-temperature processing. Incorporation during cool-down is preferred. Because Kojic Acid readily oxidizes and can discolor, consider chelation, oxygen management, and a compatible antioxidant system. In emulsions, add through the aqueous phase after the batch has cooled. Avoid uncontrolled contact with reactive metal ions.
Compatibility & Stability
Key stability issues are yellowing or browning, oxidation, pH drift, and loss of potency. Monitor color against a retained standard, pH, odor, clarity, and metal contamination. Packaging that limits light and oxygen materially improves shelf-life appearance.
R&D, Scale-Up & Quality Control
For Kojic Acid Powder, incoming and in-process QC should control identity, color, pH, solution clarity, and oxidation. Pilot transfer should lock Kojic Acid dissolution, chelator/antioxidant sequence, and cool-down exposure to air, because these variables directly influence reproducibility. Release the formulation only after no progressive browning, metal-related discoloration, or precipitation develops.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed, cool, dry, and protected from light, moisture, and excessive heat. Reseal immediately after use.
Estimated Delivery: 10–15 Business Days
Applications
Brightening serums, spot-care systems, emulsions, lotions, gels, masks, and multi-active tone-evening formulations.
Reviews
There are no reviews yet.