Description
Description
3-O-Ethyl Ascorbic Acid is an etherified vitamin C derivative in which the 3-hydroxyl group of ascorbic acid is protected by an ethyl substituent. This structural modification improves handling and oxidative stability while retaining a free-enediol system capable of participating in vitamin C-related antioxidant and tone-support pathways after topical application.
Chemical & Technical Profile
| INCI / Identity | 3-O-Ethyl Ascorbic Acid |
|---|---|
| CAS No. | 86404-04-8 |
| Molecular Formula | C8H12O6 |
| Molecular Weight | 204.18 g/mol |
| Physical Form | White to off-white crystalline powder |
| Solubility | Water-soluble; compatible with aqueous and hydroalcoholic systems |
| Functional Category | Ethylated vitamin C derivative / antioxidant skin-conditioning active |
Mechanism of Action / Technical Function
The molecule can contribute directly to antioxidant redox activity and may undergo biological conversion that increases availability of vitamin C-related activity in skin. Its formulation relevance is strongest in multi-active brightening systems because it combines aqueous compatibility with greater stability than free ascorbic acid. Published work also supports inhibition of melanogenesis-related processes, giving a mechanistic basis for tone-evening positioning.
Formulation Guidelines
Dissolve in purified water or a controlled aqueous premix before incorporation. Unlike classical L-ascorbic acid, the derivative does not require an extremely low-pH vehicle; mildly acidic systems are commonly preferred for balancing skin feel and stability. Avoid unnecessary high-temperature holds and prolonged exposure to air during processing. In electrolyte-sensitive gels, consider the total ionic contribution from all water-soluble actives. Pairing with niacinamide, N-acetyl glucosamine, Alpha-Arbutin, or humectants should be evaluated at the finished-formula pH rather than by ingredient reputation alone.
Compatibility & Stability
Monitor color, pH, clarity, odor, and active-content retention. Progressive yellowing can indicate oxidative degradation. Trace-metal control and oxygen management improve robustness, particularly in water-rich serums stored in transparent packaging.
R&D, Scale-Up & Quality Control
For 3-O-Ethyl Ascorbic Acid Powder, incoming and in-process QC should control color, pH, solution clarity, and oxidative drift. Pilot transfer should lock aqueous premix concentration, oxygen exposure, and the order of antioxidant/chelating ingredients, because these variables directly influence reproducibility.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed, dry, cool, and protected from direct light and prolonged heat. Reseal promptly after dispensing.
Estimated Delivery: 10–15 Business Days
Applications
Vitamin C serums, brightening gels, lotions, facial essences, emulsions, tone-evening products, and multi-antioxidant skin-care systems.






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