Description
Acetyl Hexapeptide-8 powder helps skincare formulators create anti-aging serums, creams, lotions, and eye products. It supports a smoother skin look and helps reduce the appearance of expression lines.
Also, brands use this cosmetic peptide in premium wrinkle-care products because it fits modern anti-aging formulas. Therefore, it works well for R&D labs, OEM manufacturers, and private label skincare brands.
Acetyl Hexapeptide-8 belongs to the Argireline®-type peptide category. However, brands should use the Argireline® name only when the supplied grade allows trademark use.
Key Benefits
Acetyl Hexapeptide-8 helps reduce the appearance of dynamic wrinkles. These lines usually appear on the forehead, around the eyes, and near expression zones.
In addition, this peptide helps improve the look of skin smoothness. As a result, the finished product can support a softer and more refined skin appearance.
Also, formulators use Acetyl Hexapeptide-8 in premium anti-aging skincare. Therefore, it fits facial serums, eye creams, wrinkle-care creams, and professional cosmetic formulas.
Product Specifications
| Item | Details |
|---|---|
| Product Name | Acetyl Hexapeptide-8 |
| INCI Name | Acetyl Hexapeptide-8 |
| CAS No. | 616204-22-9 |
| Molecular Formula | C34H60N14O12S |
| Molecular Weight | 888.992 |
| Appearance | White to off-white powder |
| Solubility | Soluble in water |
| Product Type | Cosmetic peptide active |
| Typical Use Level | 0.001–2% |
| Best Product Types | Serums, creams, lotions, and eye products |
How Acetyl Hexapeptide-8 Works
Acetyl Hexapeptide-8 supports anti-aging cosmetic formulas by helping reduce the look of expression lines. This biomimetic peptide helps improve the appearance of skin affected by repeated facial movement.
However, this ingredient does not act like an injectable treatment. Use it only in topical cosmetic products. Therefore, product claims should stay within cosmetic limits.
For best marketing language, use phrases such as “helps reduce the appearance of fine lines,” “supports smoother-looking skin,” and “helps improve the appearance of expression wrinkles.”

Recommended Use Level
| Product Type | Recommended Level |
|---|---|
| Facial serums | 0.01–2% |
| Eye creams | 0.01–1% |
| Anti-aging creams | 0.01–2% |
| Lotions | 0.01–1% |
| Professional skincare formulas | 0.01–2% |
How to Use in Formulation
First, dissolve or disperse Acetyl Hexapeptide-8 in the water phase or in a suitable water-based premix. Then, add it to the main batch during the cool-down phase.
For best results, keep the processing temperature below 40°C. Also, avoid long heating time because harsh processing may reduce peptide performance.
In addition, keep the final product pH within a suitable skincare range. Formulators commonly prefer a pH range of 4.5–7.0 for peptide-containing cosmetic products.
Finally, test the finished formula for pH, color, odor, viscosity, and stability before production.
Formulation Compatibility
Acetyl Hexapeptide-8 works well in many water-based skincare systems. For example, formulators can combine it with hyaluronic acid, glycerin, panthenol, niacinamide, other peptides, and common non-ionic emulsifier systems.
However, avoid extreme pH, high heat, and strong oxidizing systems. Also, test the final formula before scale-up because preservatives, salts, fragrance, and pH adjusters may affect product stability.
Acetyl Hexapeptide-8 Applications
Use Acetyl Hexapeptide-8 in anti-aging serums, wrinkle-care creams, eye creams, firming lotions, professional skincare products, and private label cosmetic lines.
In addition, this ingredient helps OEM/ODM manufacturers, R&D laboratories, cosmetic brands, and formulators create premium anti-aging skincare products.
Why Buy Acetyl Hexapeptide-8 From Us
We supply cosmetic-grade Acetyl Hexapeptide-8 for professional skincare formulation. Also, we provide COA, TDS, and MSDS documents upon request.
In addition, we support R&D labs, private label brands, and cosmetic manufacturers with reliable raw materials for scalable production. Therefore, this product suits both small-batch development and commercial manufacturing.
Storage and Shelf Life
Store Acetyl Hexapeptide-8 in a cool, dry place away from light. Also, close the container tightly after each use.
When you store the product under recommended conditions, the typical shelf life reaches 24 months.
Shipping Information
We offer free worldwide shipping. Delivery usually takes 10–15 business days, depending on the destination and shipping conditions.
Cosmetic Use Disclaimer
Use this product for cosmetic applications only. Do not use it to diagnose, treat, cure, or prevent any disease.






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