Description
Description
Biotinoyl Tripeptide-1 is a biotin-conjugated tripeptide used in premium scalp and hair-care formulations. The molecule combines a short peptide sequence with a biotin moiety, providing a technical platform for targeted conditioning and scalp-support concepts without relying on simple free-biotin supplementation.
Chemical & Technical Profile
| INCI / Identity | Biotinoyl Tripeptide-1 |
|---|---|
| CAS No. | 299157-54-3 |
| Molecular Formula | Peptide conjugate |
| Molecular Weight | Approx. 566 g/mol; grade-dependent |
| Physical Form | White to off-white powder |
| Solubility | Water-soluble |
| Functional Category | Biotinylated scalp- and hair-conditioning peptide |
Mechanism of Action / Technical Function
The material is commonly positioned around support of extracellular-matrix anchoring and hair-follicle environment. The peptide component is intended to interact with biological pathways associated with follicular support, while biotinylation changes molecular recognition and substantivity. Cosmetic use should remain within appearance, conditioning, and scalp-support claims rather than therapeutic hair-regrowth claims.
Formulation Guidelines
Dissolve in purified water and add during cool-down, preferably below approximately 40°C. Avoid prolonged heat, strong oxidants, extreme pH, and proteolytic ingredients. In scalp tonics, hydroalcoholic systems should be checked for peptide solubility at the final alcohol level. In shampoos, rinse-off contact time limits delivery; leave-on scalp serums generally provide a more technically rational vehicle for low-dose peptide actives.
Compatibility & Stability
Monitor pH, clarity, odor, precipitation, and peptide integrity. High electrolyte or alcohol levels can reduce solubility of some peptide grades. Preservation and package compatibility should be verified on the complete finished product.
R&D, Scale-Up & Quality Control
Biotinoyl Tripeptide-1 should be qualified against peptide identity, pH, clarity, and hydroalcoholic solubility, using a retained reference where visual change is relevant. During scale-up, document Biotinoyl Tripeptide-1 addition temperature, alcohol level, and post-addition shear and reproduce the laboratory sequence without unplanned thermal or shear exposure.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Keep tightly closed, cool, dry, and protected from light and humidity. Refrigerated storage is preferred for long-term peptide stability.
Estimated Delivery: 10–15 Business Days
Applications
Scalp serums, leave-on hair tonics, conditioners, premium hair-care treatments, eyebrow/eyelash conditioning systems, and multi-peptide scalp formulations.
Regulatory Note
For U.S. marketing, avoid finished-product claims that imply treatment of alopecia or guaranteed hair regrowth unless the product is developed within the applicable drug framework.
Reviews
There are no reviews yet.