Description
Description
Phenylethyl Resorcinol is a synthetic resorcinol derivative used in high-performance tone-evening systems. Its aromatic resorcinol nucleus and phenethyl substituent provide strong affinity for the catalytic environment of tyrosinase, making the material relevant to formulations intended to reduce the appearance of uneven pigmentation and support a more uniform visible skin tone.
Chemical & Technical Profile
| INCI / Identity | Phenylethyl Resorcinol |
|---|---|
| CAS No. | 85-27-8 |
| Molecular Formula | C14H14O2 |
| Molecular Weight | 214.26 g/mol |
| Physical Form | White to off-white crystalline powder |
| Solubility | Low water solubility; soluble in suitable glycols, alcohols, and oil-compatible systems |
| Functional Category | Tyrosinase-targeting skin-conditioning active |
Mechanism of Action / Technical Function
Phenylethyl Resorcinol acts primarily through inhibition of tyrosinase, the copper-dependent enzyme responsible for oxidation of L-tyrosine and L-DOPA during melanogenesis. The resorcinol moiety interacts efficiently with the enzyme’s catalytic copper-containing site, decreasing formation of downstream melanin intermediates. This mechanism is distinct from exfoliation-driven tone correction and makes the active especially appropriate for targeted multi-pathway brightening systems.
Formulation Guidelines
The powder should be pre-solubilized before addition to the main batch. Because direct water solubility is limited, use a compatible solvent system such as selected glycols, alcohols, or an appropriate oil-compatible carrier depending on the product architecture. Incorporate under controlled temperature and avoid prolonged heating. In emulsions, verify that the solvent package does not disturb emulsifier performance or sensory profile. In clear serums, conduct bench-scale solubility screening before scale-up and confirm that the active remains fully dissolved after cool-down and low-temperature storage.
Compatibility & Stability
Key failure modes are recrystallization, haze, progressive color shift, and loss of clarity caused by inadequate solvent capacity or temperature-dependent solubility. Monitor pH, appearance, precipitation, color, and active content where analytical capability is available. Compatibility should be evaluated with strong oxidants, metal salts, and highly acidic or alkaline systems.
R&D, Scale-Up & Quality Control
R&D qualification of Phenylethyl Resorcinol Powder should include identity, color, solvent clarity, and recrystallization.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed in a cool, dry, dark location and protect from humidity and prolonged heat during transport. Reseal immediately after dispensing.
Estimated Delivery: 10–15 Business Days
Applications
Advanced brightening serums, spot-care systems, facial emulsions, tone-evening creams, and multi-active radiance formulations.
n***s –
the more I try the better I feel.