Description
Description
Climbazole is an imidazole-derived cosmetic active used internationally in scalp-care and scalp-comfort systems.
Chemical & Technical Profile
| INCI / Identity | Climbazole |
|---|---|
| CAS No. | 38083-17-9 |
| Molecular Formula | C15H17ClN2O2 |
| Molecular Weight | 292.76 g/mol |
| Physical Form | White crystalline powder |
| Solubility | Low water solubility; soluble in suitable alcohols, glycols, surfactant systems, and organic carriers |
| Functional Category | Scalp-care cosmetic active |
Mechanism of Action / Technical Function
This biochemical mechanism explains why formulation performance depends not only on concentration but also on solubilization, deposition, and contact with the scalp surface.
Formulation Guidelines
Pre-solubilize in a compatible solvent, glycol, or surfactant concentrate before addition to the main batch. Do not expect the crystalline powder to dissolve directly in water. In clear shampoos, fragrance, electrolytes, and surfactant composition can shift solubility; conduct cloud-point and low-temperature testing after the complete formula is assembled. Incorporate at controlled temperature and avoid local supersaturation. Evaluate deposition and rinse profile in performance development.
Compatibility & Stability
Monitor precipitation, haze, color, pH, viscosity, and crystal formation. Low-temperature storage is particularly useful for revealing marginal solubility. The active does not replace the preservative system.
R&D, Scale-Up & Quality Control
For Climbazole Powder, incoming and in-process QC should control active dissolution, pH, clarity, and crystal formation. Pilot transfer should lock the climbazole solvent premix, surfactant/fragrance addition order, and final salt adjustment, because these variables directly influence reproducibility.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed, cool, dry, and protected from light and heat. Avoid moisture contamination after opening.
Estimated Delivery: 10–15 Business Days
Applications
Scalp shampoos, conditioners, scalp tonics, cleansing systems, rinse-off treatments, and professional hair-care formulations.
Regulatory Note
Formulators should establish claim eligibility and active-ingredient status for the intended market before commercialization.
Related Ingredients
Documentation & Use
- Certificate of Analysis (COA) for the lot shipped: available on request at info@pureingredients.us.
- Safety Data Sheet (SDS): available on request.
- SKU: PI-RM-0053
For cosmetic formulation use only. Not for direct application to skin.
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