Description
Description
Trans-Resveratrol is a stilbene polyphenol containing three phenolic hydroxyl groups and a conjugated trans double bond. It is used in advanced antioxidant and age-support systems where formulators require a recognizable polyphenol with strong redox chemistry but must solve the associated solubility, oxidation, and photostability challenges.
Chemical & Technical Profile
| INCI / Identity | Resveratrol |
|---|---|
| CAS No. | 501-36-0 |
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Physical Form | White to off-white or pale yellow crystalline powder |
| Solubility | Very low water solubility; soluble in ethanol, glycols, and selected solvents |
| Functional Category | Polyphenolic antioxidant / skin-conditioning active |
Mechanism of Action / Technical Function
Resveratrol can donate hydrogen equivalents to reactive radical species and stabilize the resulting phenoxyl intermediates through resonance. Beyond direct redox chemistry, experimental skin research has examined modulation of oxidative-stress and inflammatory signaling pathways. The trans isomer is the principal form used in cosmetic development, and light-driven isomerization to the cis form is therefore a relevant stability concern.
Formulation Guidelines
Do not add dry resveratrol directly to a water-rich serum. Develop a solvent or carrier system using ethanol, glycols, a solubilizer, lipid carrier, or encapsulation approach that maintains complete dissolution over the full storage temperature range. Cool-down addition is preferred. Avoid high-pH processing and unnecessary oxygen exposure. In emulsions, verify partitioning and recrystallization after cycling. When combining with vitamin C derivatives or ferulic acid, assess total solvent demand rather than assuming compatibility.
Compatibility & Stability
Monitor color, crystallization, precipitation, trans-to-cis isomerization risk, odor, and active-content retention. Opaque or UV-limiting packaging materially improves robustness. Trace-metal control is useful in complex antioxidant systems.
R&D, Scale-Up & Quality Control
For Trans-Resveratrol Powder, incoming and in-process QC should control trans-resveratrol identity, solution clarity, color, and crystal formation. Pilot transfer should lock the solvent-to-active ratio, cool-down dilution, and oxygen/light exposure, because these variables directly influence reproducibility. Release the formulation only after the system remains free of precipitate and excessive photo-oxidative color change.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed, cool, dry, and protected from direct light and oxygen. Avoid prolonged elevated temperatures during shipment.
Estimated Delivery: 10–15 Business Days
Applications
Antioxidant serums, facial emulsions, eye-area products, premium age-support treatments, and multi-polyphenol skin-care systems.
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