Description
Description
Hexapeptide-11 is a short synthetic or biotechnology-derived cosmetic peptide used in premium age-support and skin-renewal systems. Its sequence-defined nature distinguishes it from hydrolyzed proteins: performance depends on preservation of the intact hexapeptide rather than on general amino-acid or film-forming effects.
Chemical & Technical Profile
| INCI / Identity | Hexapeptide-11 |
|---|---|
| CAS No. | Peptide; grade-specific |
| Molecular Formula | Defined hexapeptide |
| Molecular Weight | Sequence-dependent |
| Physical Form | White to off-white powder |
| Solubility | Water-soluble |
| Functional Category | Signal peptide / skin-conditioning active |
Mechanism of Action / Technical Function
Hexapeptide-11 has been studied in relation to cellular signaling pathways associated with extracellular-matrix organization and age-related skin function. Cosmetic use is based on signal-peptide behavior rather than direct structural replacement of collagen or elastin. Because peptide signaling is sequence-specific, hydrolysis, oxidation, or chemical modification can reduce activity without obvious visual change.
Formulation Guidelines
Dissolve in purified water and introduce during cool-down. Avoid prolonged high temperature, strong oxidants, extreme pH, and proteolytic enzymes. In multi-active formulas, add after neutralization and after the main polymer network has developed. High concentrations of alcohol, salts, or cationic surfactants should be checked for peptide compatibility. Avoid unnecessary homogenization after peptide addition.
Compatibility & Stability
Monitor pH, clarity, color, odor, microbial quality, and peptide integrity where analytical testing is available. In emulsions, confirm that the peptide remains in the intended aqueous environment and does not adsorb excessively to packaging or suspended solids.
R&D, Scale-Up & Quality Control
R&D qualification of Hexapeptide-11 Powder should include peptide identity, solution clarity, pH, and microbial quality. For manufacturing scale-up, define and control Hexapeptide-11 dissolution, maximum addition temperature, and post-addition mixing time rather than transferring only the ingredient percentages. The batch is technically acceptable when the final serum remains clear and stable without exposing the peptide to unnecessary thermal or oxidative stress.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed, cool, dry, and protected from light and humidity. Refrigerated storage is preferred for extended storage.
Estimated Delivery: 10–15 Business Days
Applications
Anti-aging serums, moisturizers, eye-area formulations, facial gels, firming creams, and multi-peptide skin-renewal systems.
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