Description
Description
Acetyl Hexapeptide-38 is a synthetic six-amino-acid peptide used in contouring and volumizing cosmetic concepts. Unlike expression-line peptides, this material is positioned around signaling pathways associated with adipocyte differentiation and lipid storage, making its technical use distinct from classical collagen-focused or neuromodulating peptide systems.
Chemical & Technical Profile
| INCI / Identity | Acetyl Hexapeptide-38 |
|---|---|
| CAS No. | 1400634-44-7 |
| Molecular Formula | Synthetic hexapeptide |
| Molecular Weight | Sequence-dependent |
| Physical Form | White to off-white powder |
| Solubility | Water-soluble |
| Functional Category | Adipogenesis-signaling cosmetic peptide |
Mechanism of Action / Technical Function
Research and commercial peptide technology associate Acetyl Hexapeptide-38 with up-regulation of transcriptional pathways involved in adipogenesis, including PGC-1α-related signaling. In cosmetic use, the intended outcome is improvement in the appearance of local volume and contour rather than medical tissue growth. Sequence integrity is essential because the biological activity is peptide-receptor/signaling dependent.
Formulation Guidelines
Dissolve in purified water and add during cool-down below approximately 40°C whenever possible. Avoid prolonged heat, strong oxidants, proteolytic enzymes, and extreme pH. In emulsions, add after homogenization to limit mechanical and thermal stress. Contour products often contain high oil or silicone levels; verify that the aqueous peptide phase remains uniformly distributed and that the emulsion does not separate during cycling.
Compatibility & Stability
Monitor pH, color, odor, clarity, microbial stability, and emulsion integrity. Avoid assuming that a visually stable cream preserves peptide activity; analytical or performance testing should be used when available. High preservative or solvent levels should be checked for peptide compatibility.
R&D, Scale-Up & Quality Control
Critical quality attributes for Acetyl Hexapeptide-38 Powder include peptide identity, pH, clarity, and emulsion distribution. The production record should fix Acetyl Hexapeptide-38 cool-down addition, post-homogenization shear, and aqueous-phase uniformity; otherwise a chemically correct formula can still show batch-to-batch physical variation. Before release, verify that the contour formula remains homogeneous without peptide precipitation or preservative incompatibility.
Packaging, Shipping & Storage
Supplied in a sealed aluminum pouch. Store tightly closed, cool, dry, and protected from light and humidity. Refrigerated storage is preferred for long-term peptide quality.
Estimated Delivery: 10–15 Business Days
Applications
Body-contour creams, bust-care products, lip-contour systems, facial-volumizing serums, emulsions, and specialty peptide formulations.
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