Description
Mequinol (4-Methoxyphenol) is a synthetic phenolic compound used as a specialized cosmetic raw material in professional skin tone–adjusting cosmetic formulation. Known chemically as a methoxy-substituted phenol, this skincare ingredient is utilized in controlled topical systems for its melanin pathway–modulating properties within regulated cosmetic frameworks.
INCI Name: Mequinol
Chemical Name: 4-Methoxyphenol
CAS Number: 150-76-5
Chemical Classification: Substituted phenolic compound (aromatic ether phenol derivative)
Molecular Formula: C₇H₈O₂
Physical Form: White to off-white crystalline powder
Origin: Synthetic
Solubility: Slightly soluble in water; soluble in alcohols, glycols, and organic solvents
Typical Usage Level: Subject to strict regional regulation; typically ≤0.5% in cosmetic contexts (verify local laws)
pH Stability Range: Most stable in slightly acidic systems (pH 4.0–6.0)
Storage Conditions: Store tightly sealed, protected from light, heat, and air; recommended below 25°C
Mequinol is a highly regulated personal care ingredient. Its use in cosmetic formulation must comply with applicable regional cosmetic regulations (EU, FDA cosmetic framework, ASEAN, etc.). It is intended strictly for professional use and not for over-the-counter medical applications unless separately approved under pharmaceutical regulations.
Key Benefits in Cosmetic Formulation
Mequinol is recognized in cosmetic science literature for its ability to influence visible skin tone appearance when used within regulatory concentration limits.
1. Melanin Pathway Interaction (Cosmetic Context)
As a phenolic analog structurally related to hydroquinone derivatives, Mequinol interacts with the melanin synthesis pathway at the enzymatic level. In cosmetic-grade applications and approved concentrations, it supports a more uniform-looking skin tone.
2. Targeted Tone Appearance Adjustment
In professional cosmetic formulation, Mequinol may be incorporated into localized treatment systems designed to improve the appearance of uneven pigmentation.
3. Controlled Performance in Stabilized Systems
When properly stabilized with antioxidants and packaged appropriately, Mequinol maintains acceptable formulation stability for cosmetic use.
4. Synergy with Antioxidant Systems
To improve oxidative stability, formulators often combine this cosmetic raw material with stabilizers such as ascorbic acid derivatives or chelating agents.
All benefits described are cosmetic in nature. No therapeutic, medical, or drug claims are implied.
How to Use in Cosmetic Formulation
Recommended Usage Level of Mequinol (4-Methoxyphenol)
Due to regulatory sensitivity, the recommended usage level of Mequinol depends entirely on jurisdiction. In cosmetic contexts where permitted:
Spot-treatment systems: ≤0.5%
Professional-use formulations only
Always confirm regulatory compliance prior to commercialization
How to Use Mequinol (4-Methoxyphenol) in Skincare
Pre-dissolve in ethanol or propylene glycol before incorporation.
Add during cool-down phase below 40°C.
Maintain formulation pH between 4.5–5.5.
Incorporate antioxidants and oxygen-barrier packaging.
Conduct full safety and stability testing.
Because Mequinol is oxidation-sensitive, exposure to light and air must be minimized. Use opaque, airless packaging for finished formulations.
Stability Considerations
Sensitive to oxidation
May discolor upon air exposure
Requires chelating and antioxidant support
Avoid alkaline systems
When developing Mequinol in cosmetic formulation, comprehensive compatibility and photostability testing is mandatory.
Applications
Mequinol (4-Methoxyphenol) cosmetic grade is suitable for:
Professional spot-correcting systems
Controlled brightening formulations
Dermatological cosmetic product development
Regulated aesthetic product lines
This cosmetic raw material is not suitable for mass-market, unrestricted consumer products without confirming regional compliance.
Manufacturers seeking to buy Mequinol (4-Methoxyphenol) cosmetic grade bulk should ensure their regulatory team verifies permitted use conditions.
Technical Specifications
Mechanism of Action on Skin (Cosmetic Level)
Interacts with melanin synthesis pathway
Competes at tyrosinase-related processes
Supports more even-looking skin tone
Used in controlled pigmentation appearance management systems
All activity described refers to cosmetic surface-level effects and does not constitute medical treatment.
Regulatory Considerations
Mequinol is highly regulated globally. In some regions, it is restricted or categorized under medicinal product frameworks when used for depigmentation. Cosmetic manufacturers must:
Verify local concentration limits
Review annex restrictions (e.g., EU Cosmetic Regulation Annexes)
Conduct safety assessments
Ensure compliant labeling
This personal care ingredient is supplied strictly as a cosmetic raw material for authorized professional use only.
Why Choose Us as Your Bulk Cosmetic Raw Material Supplier
As a specialized bulk supplier of high-purity cosmetic grade actives, we provide:
1. Verified Quality Standards
Consistent purity
COA, TDS, MSDS available
Batch traceability
2. Regulatory Support
Our regulatory team assists with:
Documentation review
Compliance guidance
International regulatory alignment
3. Technical Expertise
Senior cosmetic chemists support:
Stability system design
Antioxidant stabilization strategies
Packaging recommendations
Scale-up consultation
4. Professional B2B Focus
We supply exclusively to:
Licensed manufacturers
R&D laboratories
Dermatological cosmetic brands
Professional-use formulation facilities
When you buy Mequinol (4-Methoxyphenol) cosmetic grade bulk from us, you receive a technically validated cosmetic raw material supported by regulatory awareness and industrial-grade quality control.
Shipping Information
Free shipping worldwide. Shipping remains free permanently. Delivery time: 10–15 business days.
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